Document Detail


The use of technology to reduce hypoglycemia.
MedLine Citation:
PMID:  20877251     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For children as well as adults with diabetes, hypoglycemia and the fear it generates limit attainment of glycemic targets. In this paper we discuss advances in technology that have the potential to prevent or limit exposure to hypoglycemia. Improvements in insulin delivery, different types of boluses and bolus advisors assisting patients in deciding doses, software data downloads to observe patterns and continuous glucose sensors with hypoglycemia alarms warning of impending hypoglycemia may all be able to reduce hypoglycemia burden and are now available for clinical use. Advances in the integration of continuous glucose monitoring and insulin pumps already allow automated suspension of insulin delivery during hypoglycemia to limit its severity and duration. Current developments include overnight and hybrid closed loop insulin delivery systems, dual hormone delivery and other modifications to existing therapies that offer the potential to reduce the risk of hypoglycemia for people with diabetes.
Authors:
Pratik Choudhary; Stephanie A Amiel
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric endocrinology reviews : PER     Volume:  7 Suppl 3     ISSN:  1565-4753     ISO Abbreviation:  Pediatr Endocrinol Rev     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-09-29     Completed Date:  2010-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101202124     Medline TA:  Pediatr Endocrinol Rev     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  384-95     Citation Subset:  IM    
Affiliation:
King's College London School of Medicine, Denmark Hill Campus, 3rd Floor, Weston Education Centre, Cutcombe Lane, Denmark Hill, London, SE5 9RJ.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Glucose / analysis*
Child
Diabetes Mellitus, Type 1 / blood,  drug therapy*
Humans
Hypoglycemia / blood,  prevention & control*
Insulin / administration & dosage*
Insulin Infusion Systems*
Monitoring, Ambulatory / methods
Chemical
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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