Document Detail

The use of taxanes in choriocarcinoma; a case report and review of the literature.
MedLine Citation:
PMID:  15297209     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Both preclinical data and case reports support the use of taxanes for high-risk metastatic choriocarcinoma. CASE: We report the case of a 31-year-old with metastatic choriocarcinoma who required 3rd-line treatment with a paclitaxel-cisplatin-based regimen. She achieved a complete response and remains relapse-free 21 months after her last dose of chemotherapy. CONCLUSION: The literature suggests that paclitaxel contributes significantly to the treatment of choriocarcinoma and its use should be explored further. This is the first case report formally reporting its combination with cisplatin.
A M Joshua; J R Carter; P Beale
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Gynecologic oncology     Volume:  94     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-06     Completed Date:  2004-09-14     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  581-3     Citation Subset:  IM    
Department of Medical Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Missenden Road, Campderdown 2050, Sydney, Australia.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Choriocarcinoma / drug therapy*
Cisplatin / administration & dosage
Paclitaxel / administration & dosage,  therapeutic use*
Uterine Neoplasms / drug therapy*
Reg. No./Substance:
15663-27-1/Cisplatin; 33069-62-4/Paclitaxel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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