Document Detail

The use of selective serotonin reuptake inhibitors in young children with pervasive developmental disorders: some clinical observations.
MedLine Citation:
PMID:  8862855     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the effects of a new group of psychotropic medications, the selective serotonin reuptake inhibitors (SSRIs), on some symptoms of young children (under 7 years old) with pervasive developmental disorders (PDD). METHOD: Open clinical trial. RESULTS: Medications produced positive results in half the children, particularly those with obsessional, repetitive, and anxiety symptoms. The medication was discontinued in half the children: one-quarter for worsening of symptoms and the other quarter for doubtful side effects. CONCLUSIONS: SSRIs may have a role to play in ameliorating some symptoms of PDD. Further studies with standardized measurements, however, are needed to elucidate which children and what symptoms could benefit from which medication.
G A Awad
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian journal of psychiatry. Revue canadienne de psychiatrie     Volume:  41     ISSN:  0706-7437     ISO Abbreviation:  Can J Psychiatry     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-01-06     Completed Date:  1997-01-06     Revised Date:  2007-08-01    
Medline Journal Info:
Nlm Unique ID:  7904187     Medline TA:  Can J Psychiatry     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  361-6     Citation Subset:  IM    
Department of Psychiatry, Hospital for Sick Children, Toronto, ON.
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MeSH Terms
Child, Preschool
Developmental Disabilities / drug therapy*
Serotonin Uptake Inhibitors / adverse effects,  therapeutic use*
Reg. No./Substance:
0/Serotonin Uptake Inhibitors

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