Document Detail

On the use of scaling and clustering in the study of semantic deficits.
MedLine Citation:
PMID:  12803435     Owner:  NLM     Status:  MEDLINE    
In the past decade, several studies have used scaling and clustering techniques to document semantic storage deficits in patients with Alzheimer's disease and in schizophrenia. In this article the authors argued that many of the conclusions drawn from these studies are unjustified by the data. They reviewed the methodology used in these studies and presented data from simulation studies to further investigate the validity of their conclusions. The authors elaborate on the criteria needed to exclude alternative accounts of the data and present empirical data from patients with Alzheimer's disease and normal control participants to demonstrate that analyses of the patients' proximity data do not provide unambiguous evidence for a generalized semantic storage deficit.
Gert Storms; Trinette Dirikx; Jos Saerens; Sonja Verstraeten; Peter P De Deyn
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Neuropsychology     Volume:  17     ISSN:  0894-4105     ISO Abbreviation:  Neuropsychology     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-06-13     Completed Date:  2003-07-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8904467     Medline TA:  Neuropsychology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  289-301     Citation Subset:  IM    
Department of Psychology, University of Leuven, Belgium.
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MeSH Terms
Aged, 80 and over
Alzheimer Disease / psychology*
Cluster Analysis
Data Interpretation, Statistical*
Memory Disorders / psychology*
Memory, Short-Term / physiology*
Neuropsychological Tests
Comment In:
Neuropsychology. 2003 Apr;17(2):310-1; discussion 323-9   [PMID:  12803438 ]
Neuropsychology. 2003 Apr;17(2):312-4; discussion 323-9   [PMID:  12803439 ]
Neuropsychology. 2003 Apr;17(2):315-7; discussion 323-9   [PMID:  12803440 ]
Neuropsychology. 2003 Apr;17(2):321-2; discussion 323-9   [PMID:  12803442 ]
Neuropsychology. 2003 Apr;17(2):306-9; discussion 323-9   [PMID:  12803437 ]
Neuropsychology. 2003 Apr;17(2):318-20; discussion 323-9   [PMID:  12803441 ]
Neuropsychology. 2003 Apr;17(2):302-5; discussion 323-9   [PMID:  12803436 ]

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