| The use of a reference allergenic extract in the evaluation of allergen products. | |
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MedLine Citation:
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PMID: 4003725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two commercially available mugwort (Artemisia vulgaris (Av] pollen extracts Av-ALK and Av-PS were compared with a dialysed reference mugwort pollen extract (Av-REF) by means of crossed immunoelectrophoresis (CIE), crossed radio immunoelectrophoresis (CRIE), RAST-inhibition, RAST-screening and skin prick test. Av-ALK and Av-PS both contained approximately half the number of precipitation arcs detectable in Av-REF, and Av-PS seemed to lack two intermediate allergens and two minor allergens, while Av-ALK seemed to lack one minor allergen. The RAST-inhibition curve obtained for Av-PS did not parallel the curves obtained for Av-ALK and Av-REF, indicating that the allergen composition of Av-PS differs from that of the others. Further, RAST-screening experiments support the CIE observation that Av-PS seemed to lack two of the intermediate allergens. The HEP values determined for Av-ALK and Av-PS diverge considerably from those stated by the manufacturers. The results obtained demonstrate that the outcome of a comparison between a reference allergenic extract and allergenic products depends very much on the method employed. |
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Authors:
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L Ingemann; H Formgren; H Løwenstein; H Ipsen |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Allergy Volume: 40 ISSN: 0105-4538 ISO Abbreviation: Allergy Publication Date: 1985 May |
Date Detail:
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Created Date: 1985-07-24 Completed Date: 1985-07-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7804028 Medline TA: Allergy Country: DENMARK |
Other Details:
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Languages: eng Pagination: 273-81 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Allergens
/
analysis,
standards* Animals Humans Immunoelectrophoresis, Two-Dimensional Pollen / immunology Rabbits Radioallergosorbent Test Reference Standards Skin Tests |
| Chemical | |
Reg. No./Substance:
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0/Allergens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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