Document Detail

The use of nuclear magnetic resonance for assessment of time variation in composition of human milk and colostrum: a case study during pregnancy and post-partum.
MedLine Citation:
PMID:  12613390     Owner:  NLM     Status:  MEDLINE    
Nuclear Magnetic Resonance (NMR) Spectra were collected on milk and colostrum obtained from the author during the pregnancy and post-partum periods for two births. Peak features in the downfield region, containing antibody and aromatic resonances (6.0 to 9.0 ppm), varied over time. This time variation pattern, while nearly identical for milk following the author's two births, differed dramatically from the colostrum of another woman in labor. A possible pattern unique to each woman should be further investigated by monitoring NMR spectra on a larger sample. Downfield peak pattern variations were less intense between five women in later stages of lactation. Other spectral regions showed only minor variations with time and patterns did not differ significantly. These five women excreted proteins and/or small aromatic compounds in a time variant pattern assessable with NMR spectrocopy.
Bethany S Bechtel
Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Indian journal of physiology and pharmacology     Volume:  46     ISSN:  0019-5499     ISO Abbreviation:  Indian J. Physiol. Pharmacol.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2003-03-04     Completed Date:  2003-08-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374707     Medline TA:  Indian J Physiol Pharmacol     Country:  India    
Other Details:
Languages:  eng     Pagination:  279-86     Citation Subset:  IM    
University of Florida, Department of Chemistry, PO Box 117200, Gainesville, Florida 32611-7200, USA.
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MeSH Terms
Colostrum / chemistry*
Labor, Obstetric / physiology*
Lactation / physiology
Magnetic Resonance Spectroscopy
Milk, Human / chemistry*
Postpartum Period / physiology*
Time Factors

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