Document Detail

The use of a new viscoelastic substance combined with anaesthetic in cataract surgery by phacoemulsification.
MedLine Citation:
PMID:  16550876     Owner:  NLM     Status:  MEDLINE    
AIM OF THE STUDY: To compare and estimate the safety and efficacy of a new viscoelastic substance combined with anaesthetic used in phacoemulsification surgery. METHOD: Eight hundred seventy-four patients observed at the Department of Ophthalmology and the Department of Family Medicine of the General State Hospital of Nikea-Piraeus (Greece) submitted to a phacoemulsification surgery for cataract during a six-month period were randomly divided into two groups of 437 patients each. All patients were operated using the same scheme of anesthesia, consisting of ropivacaine drops 0.75% and lidocaine gel 2% immediately before surgery. Viscoelastic without anesthetic was used during the operation of the patients of group 1, while the new viscoelastic with anesthetic (sodium hyaluronate 1.5% and lidocaine 1%) (viscoanesthetic) was used in group 2. No intravenous sedation was given to either group. Patients were asked to complete a questionnaire including irritation or pain sensation during various phases of the operation, after the operation, as well as the degree of satisfaction from the anesthesia scheme. The participating surgeons were called to estimate post-operative corneal edema. RESULTS: In the first group of patients (viscoelastic without anesthetic) 15.6% of them reported pain during intraocular lens insertion, 24.6% reported burning sensation during acetylcholine injection, 17.4% reported pain during placement of the corneal suture, 4.1% immediate postoperative pain and 1.8% night pain. In the second group of patients (viscoelastic with anesthetic) the percentages were 1.8%, 3.2%, 4.3%, 3.6% and 1.4% respectively. 78.9% of the first group and 82.1% of the second group had no corneal edema on the first postoperative day. 91.1% of the patients of the first group and 97.3% of the second group were satisfied. CONCLUSION: The new combination of viscoelastic and anesthetic is a safe and efficient choice for the cataract surgeon who uses only anesthetic drops for cataract operations. It minimizes patients' complaints and helps in achieving better cooperation during cataract surgery.
Panagiotis Bournas; Nicolas Condilis; Dimitra Lioumi; Dimitrios Kanellas; Konstantinos Syndikakis; Emmanuel Vaikoussis
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Annali italiani di chirurgia     Volume:  76     ISSN:  0003-469X     ISO Abbreviation:  Ann Ital Chir     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2006-03-22     Completed Date:  2006-04-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372343     Medline TA:  Ann Ital Chir     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  383-8; discussion 388-9     Citation Subset:  IM    
Department of Ophthalmology, General State Hospital of Nikaia, Piraeus, Greece.
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MeSH Terms
Adjuvants, Immunologic / administration & dosage*
Amides / administration & dosage*
Anesthesia, Local / methods*
Anesthetics, Local / administration & dosage*
Double-Blind Method
Hyaluronic Acid / administration & dosage*
Lidocaine / administration & dosage*
Ophthalmic Solutions
Pain, Postoperative / prevention & control
Patient Satisfaction
Phacoemulsification / methods*
Reg. No./Substance:
0/Adjuvants, Immunologic; 0/Amides; 0/Anesthetics, Local; 0/Ophthalmic Solutions; 137-58-6/Lidocaine; 84057-95-4/ropivacaine; 9004-61-9/Hyaluronic Acid

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