Document Detail


The use of neuroimaging to study behavior in patients with epilepsy.
MedLine Citation:
PMID:  18078790     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Structural and functional neuroimaging continues to play an increasing role in the presurgical evaluation of patients with epilepsy. In addition to its value in localizing the epileptogenic zone and eloquent cortex, neuroimaging is contributing to our understanding of mood comorbidity in epilepsy. Although the vast majority of research has focused on patients with temporal lobe epilepsy (TLE), neuroimaging studies of patients with extratemporal epilepsy and primary generalized epilepsy are increasing in number. In this review, structural and functional imaging modalities that have received considerable research attention in recent years are reviewed, and their strengths and limitations for understanding behavior in epilepsy are assessed. In addition, advances in multimodal imaging are discussed along with their potential application to the presurgical evaluation of patients with seizure disorders.
Authors:
Carrie R McDonald
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2007-12-19
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  12     ISSN:  1525-5050     ISO Abbreviation:  Epilepsy Behav     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-03-24     Completed Date:  2008-06-17     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  600-11     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. camcdonald@ucsd.edu
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MeSH Terms
Descriptor/Qualifier:
Behavior*
Brain Mapping*
Cerebral Cortex / metabolism,  pathology
Epilepsy / metabolism,  pathology*,  psychology
Humans
Magnetic Resonance Imaging / methods
Magnetoencephalography / methods
Temporal Lobe / metabolism,  pathology*
Grant Support
ID/Acronym/Agency:
K23 NS056091-02/NS/NINDS NIH HHS; K23NS056091/NS/NINDS NIH HHS
Comments/Corrections

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