Document Detail

The use of medications for inflammatory bowel disease during pregnancy and nursing.
MedLine Citation:
PMID:  16144504     Owner:  NLM     Status:  MEDLINE    
Inflammatory bowel disease includes two primary disorders, ulcerative colitis and Crohn's disease. These diseases mainly affect young adults, with a peak occurrence between 15 and 25 years of age. The causes of these diseases are largely unknown, with current treatments targeted against the heightened inflammatory response witnessed in the intestinal mucosa of both conditions. With the peak age ranges for pregnancy and inflammatory bowel disease overlapping, it is important to weigh the benefits of treating a mother during pregnancy against the potential risks to the fetus and the course of the pregnancy. This review examines the current safety data on medications used in women with inflammatory bowel disease during pregnancy.
Jenny Sauk; Sunanda Kane
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  6     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-07     Completed Date:  2006-06-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  1833-9     Citation Subset:  IM    
Department of Medicine, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA.
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MeSH Terms
Adrenal Cortex Hormones / adverse effects,  therapeutic use*
Anti-Inflammatory Agents, Non-Steroidal / adverse effects,  therapeutic use*
Azathioprine / adverse effects,  therapeutic use
Breast Feeding
Clinical Trials as Topic
Colitis, Ulcerative / complications,  drug therapy
Crohn Disease / complications,  drug therapy
Fetus / drug effects
Immunosuppressive Agents / adverse effects,  therapeutic use*
Inflammatory Bowel Diseases / complications,  drug therapy*
Milk, Human / metabolism
Pregnancy Complications / drug therapy*
Pregnancy Outcome
Prenatal Care
Sulfasalazine / adverse effects,  therapeutic use
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Immunosuppressive Agents; 446-86-6/Azathioprine; 599-79-1/Sulfasalazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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