Document Detail


The use of a linear Halbach array combined with a step-SPLITT channel for continuous sorting of magnetic species.
MedLine Citation:
PMID:  21399709     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Quadrupole Magnetic Sorter (QMS), employing an annular flow channel concentric with the aperture of a quadrupole magnet, is well established for cell and particle separations. Here we propose a magnetic particle separator comprising a linear array of cylindrical magnets, analogous to the array proposed by Klaus Halbach, mated to a substantially improved form of parallel-plate SPLITT channel, known as the step-SPLITT channel. While the magnetic force and throughput are generally lower than for the QMS, the new separator has advantages in ease of fabrication and the ability to vary the magnetic force to suit the separands. Preliminary experiments yield results consistent with prediction and show promise regarding future separations of cells of biomedical interest.
Authors:
Mauricio Hoyos; Lee Moore; P Stephen Williams; Maciej Zborowski
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of magnetism and magnetic materials     Volume:  323     ISSN:  0304-8853     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-3-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101314425     Medline TA:  J Magn Magn Mater     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1384-1388     Citation Subset:  -    
Affiliation:
Laboratoire de Physique et Mécanique des Milieux Hétérogènes, ESPCI, Paris, 75005, France.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 CA062349-17//NCI NIH HHS

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