Document Detail


The use and limitations of current 'standard' toxicological data packages in the setting of acute reference doses.
MedLine Citation:
PMID:  10983585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To perform risk assessments for short term dietary intakes of pesticides it is necessary to determine an acceptable level of exposure from the available toxicity studies. This type of assessment is a relatively new development in regulatory toxicology and often the studies currently available are not optimal for such uses. The strengths and weaknesses of currently performed study types are presented. Consideration of the entire toxicity data base is essential.
Authors:
I C Dewhurst
Related Documents :
14757105 - Toxicology investigations with cell culture systems: 20 years after.
7826665 - Risk assessment for possible effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) and ...
9230455 - A computer model and program for xenobiotic disposition during pregnancy.
22060695 - An international study on the importance of androstenone and skatole for boar taint: i....
17544425 - Application of gaussian processes for black-box modelling of biosystems.
15222295 - Comparison of prosthetic valve hydrodynamic function: objective testing using statistic...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food additives and contaminants     Volume:  17     ISSN:  0265-203X     ISO Abbreviation:  Food Addit Contam     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-10-04     Completed Date:  2000-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8500474     Medline TA:  Food Addit Contam     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  611-5     Citation Subset:  IM    
Affiliation:
i.c.dewhurst@psd.maff.gsi.gov.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Data Interpretation, Statistical
Dogs
Food Contamination*
Humans
Maximum Allowable Concentration
Pesticide Residues* / toxicity
Reference Standards
Research Design
Risk Assessment / methods
Chemical
Reg. No./Substance:
0/Pesticide Residues

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A practical application of probabilistic modelling in assessment of dietary exposure of fruit consum...
Next Document:  Acute reference doses: theory and practical approaches.