Document Detail


The use of levetiracetam in refractory status epilepticus.
MedLine Citation:
PMID:  16426869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Six patients with status epilepticus (SE) of various etiologies refractory to at least two antiepileptic drugs (AEDs) had complete cessation of their seizures following administration of oral levetiracetam (LEV). Seizure types included convulsive, focal, and nonconvulsive status epilepticus. Effective doses of levetiracetam ranged from 500 to 3000 mg/day, achieving seizure control within 12-96 h. No significant adverse events were noted. Adjunctive levetiracetam should be considered for patients with status epilepticus unresponsive to initial therapy.
Authors:
Nitin C Patel; Ivan R Landan; Jeffrey Levin; Jerzy Szaflarski; Andrew N Wilner
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-01-19
Journal Detail:
Title:  Seizure : the journal of the British Epilepsy Association     Volume:  15     ISSN:  1059-1311     ISO Abbreviation:  Seizure     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-21     Completed Date:  2006-05-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9306979     Medline TA:  Seizure     Country:  England    
Other Details:
Languages:  eng     Pagination:  137-41     Citation Subset:  IM    
Affiliation:
Pediatric Neurology, M756, MSB, DC058.00, One Hospital Drive Columbia, MO 65212, USA. PatelN@health.missouri.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged, 80 and over
Anticonvulsants / administration & dosage,  therapeutic use*
Dose-Response Relationship, Drug
Drug Therapy, Combination
Female
Humans
Male
Middle Aged
Piracetam / administration & dosage,  analogs & derivatives*,  therapeutic use
Status Epilepticus / drug therapy*
Chemical
Reg. No./Substance:
0/Anticonvulsants; 33996-58-6/etiracetam; 7491-74-9/Piracetam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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