Document Detail

The use of iron-fortified wheat flour to reduce anemia among the estate population in Sri Lanka.
MedLine Citation:
PMID:  15060899     Owner:  NLM     Status:  MEDLINE    
The use of flour fortified with 66 mg/kg of electrolytic or reduced iron to reduce the prevalence of anemia was determined in a two-year, double-blind, controlled trial. The trial was conducted in Sri Lanka among preschoolers between 9 and 71 months old, primary schoolers 6 to 11 years old, and nonpregnant women. At baseline, 18.4% of the preschoolers had low hemoglobin (Hb) concentrations. Neither electrolytic nor reduced iron had an effect on Hb concentration among preschoolers. Only 7% of the primary schoolers were anemic at the start of the trial and, again, fortification had no effect on Hb concentration. Twenty-nine percent of women had a low Hb at outset and there was no evidence that fortification had an effect on Hb in this group. The findings from this study suggest that fortification of flour with electrolytic iron or reduced iron was not beneficial in reducing anemia in this population. This was probably due to the low prevalence of anemia and low bioavailability of the fortificant iron. Fortification with either iron fortificant was acceptable.
P Nestel; R Nalubola; R Sivakaneshan; A R Wickramasinghe; S Atukorala; T Wickramanayake
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition     Volume:  74     ISSN:  0300-9831     ISO Abbreviation:  Int J Vitam Nutr Res     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-04-05     Completed Date:  2005-03-15     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  1273304     Medline TA:  Int J Vitam Nutr Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  35-51     Citation Subset:  IM    
University of Peradeniya.
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MeSH Terms
Age Factors
Analysis of Variance
Anemia / blood,  epidemiology,  prevention & control*
Biological Availability
Child, Preschool
Developing Countries
Double-Blind Method
Flour / statistics & numerical data*
Food, Fortified / statistics & numerical data*
Hemoglobins / analysis
Iron, Dietary / administration & dosage*
Rural Population
Sri Lanka
Treatment Outcome
Reg. No./Substance:
0/Hemoglobins; 0/Iron, Dietary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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