Document Detail


The use of intraventricular thrombolytics in intraventricular hemorrhage.
MedLine Citation:
PMID:  17553525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intraventricular hemorrhage (IVH) is associated with a high mortality and morbidity. Patients with this disorder may now be offered the possibility of treatment. This treatment comes in the form of intraventricular thrombolytics. At present a large randomized trial is testing the efficacy of intraventricular rt-PA in IVH in the setting of intracranial hemorrhage (ICH) . Preliminary data suggests that it may be successful in patients with IVH in this setting. This trial is the accumulation of animal and human trials completed over the last 20 years.
Authors:
Paul Nyquist; Daniel F Hanley
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-06-05
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  261     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-09-03     Completed Date:  2007-11-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  84-8     Citation Subset:  IM    
Affiliation:
Neurology and Anesthesia Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore Maryland, 21287-7840, USA. pnyquis1@jhmi.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Cerebral Hemorrhage / drug therapy*
Cerebral Ventricles*
Clinical Trials as Topic
Disease Models, Animal
Humans
Injections, Intraventricular
Thrombolytic Therapy* / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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