Document Detail


The use of intranasal anticholinergic agents in the treatment of nonallergic perennial rhinitis.
MedLine Citation:
PMID:  1460209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nonallergic perennial rhinitis is a heterogenous disorder. Although the underlying cause is unknown, there is evidence of an autonomic imbalance with parasympathetic hyperreactivity in affected persons. We review this evidence and the role of ipratropium bromide, an anticholinergic drug with topical activity, in the management of nonallergic perennial rhinitis. The pharmacologic features, safety, and efficacy of ipratropium bromide are reviewed.
Authors:
M R Borts; H M Druce
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of allergy and clinical immunology     Volume:  90     ISSN:  0091-6749     ISO Abbreviation:  J. Allergy Clin. Immunol.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-01-12     Completed Date:  1993-01-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  1275002     Medline TA:  J Allergy Clin Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1065-70     Citation Subset:  AIM; IM    
Affiliation:
Division of Allergy and Immunology, St. Louis University School of Medicine, MO 63104-1028.
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MeSH Terms
Descriptor/Qualifier:
Administration, Intranasal
Humans
Ipratropium / administration & dosage,  pharmacology
Nasal Provocation Tests
Parasympatholytics / administration & dosage*
Rhinitis / diagnosis,  drug therapy*,  physiopathology
Chemical
Reg. No./Substance:
0/Parasympatholytics; 60205-81-4/Ipratropium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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