| The use of intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction: data from the National Registry of Myocardial Infarction 2. | |
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MedLine Citation:
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PMID: 11376306 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Cardiogenic shock complicating acute myocardial infarction (AMI) remains the leading cause of death in patients hospitalized with AMI. Although several studies have demonstrated the importance of establishing and maintaining a patent infarct-related artery, it remains unclear as to whether intra-aortic balloon counterpulsation (IABP) provides incremental benefit to reperfusion therapy. The purpose of this study was to determine whether IABP use is associated with lower in-hospital mortality rates in patients with AMI complicated by cardiogenic shock in a large AMI registry. METHODS: We evaluated patients participating in the National Registry of Myocardial Infarction 2 who had cardiogenic shock at initial examination or in whom cardiogenic shock developed during hospitalization (n = 23,180). RESULTS: The mean age of patients in the study was 72 years, 54% were men, and the majority were white. The overall mortality rate in all patients who had cardiogenic shock or in whom cardiogenic shock developed was 70%. IABP was used in 7268 (31%) patients. IABP use was associated with a significant reduction in mortality rates in patients who received thrombolytic therapy (67% vs 49%) but was not associated with any benefit in patients treated with primary angioplasty (45% vs 47%). In a multivariate model, the use of IABP in conjunction with thrombolytic therapy decreased the odds of death by 18% (odds ratio, 0.82; 95% confidence interval, 0.72 to 0.93). CONCLUSIONS: Patients with AMI complicated by cardiogenic shock may have substantial benefit from IABP when used in combination with thrombolytic therapy. |
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Authors:
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H V Barron; N R Every; L S Parsons; B Angeja; R J Goldberg; J M Gore; T M Chou; |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American heart journal Volume: 141 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-05-28 Completed Date: 2001-06-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: United States |
Other Details:
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Languages: eng Pagination: 933-9 Citation Subset: AIM; IM |
Affiliation:
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University of California, San Francisco, USA. barron.hal@gene.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty Cohort Studies Female Humans Intra-Aortic Balloon Pumping / statistics & numerical data* Male Myocardial Infarction / mortality, surgery, therapy Registries Retrospective Studies Shock, Cardiogenic / mortality*, surgery, therapy* Thrombolytic Therapy United States / epidemiology |
| Comments/Corrections | |
Comment In:
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Am Heart J. 2001 Jun;141(6):889-92
[PMID:
11376300
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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