Document Detail

The use of injectable collagens for aesthetic rejuvenation.
MedLine Citation:
PMID:  17055395     Owner:  NLM     Status:  MEDLINE    
Bovine collagen was approved by the Food and Drug Administration in 1982 and since that time has remained a primary filler of choice for soft-tissue augmentation of dermal defects. During the past decade, however, perhaps mirroring the growth and overwhelming acceptance of botulinum toxin for wrinkle reduction, there has been an increase in demand and availability of new injectable filler products. A partial list includes the ever-expanding class of hyaluronans (hyaluronic acids), calcium hydroxylapatite, polymethylmethacrylate, poly-L-lactic acid, and silicone oil. There are many more on the immediate horizon that are under investigation both abroad and in the United States. Nevertheless, the collagen family of agents, regardless of their source of derivation, remain a reliable and useful alternative. They have an unparalleled record of safety and efficacy; they have different formulations, which makes them amenable to many indications and user friendly for the physician. And, for patient, the admixture of local anesthesia reduces the discomfort of the injection procedure.
Seth L Matarasso
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in cutaneous medicine and surgery     Volume:  25     ISSN:  1085-5629     ISO Abbreviation:  Semin Cutan Med Surg     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-10-23     Completed Date:  2007-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9617260     Medline TA:  Semin Cutan Med Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  151-7     Citation Subset:  IM    
Department of Dermatology, University of California School of Medicine, San Francisco, CA, USA.
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MeSH Terms
Biocompatible Materials / administration & dosage,  adverse effects
Collagen / administration & dosage*,  adverse effects
Cosmetic Techniques*
Injections, Subcutaneous
Reg. No./Substance:
0/Biocompatible Materials; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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