Document Detail

The use of inhaled aerosolized prostacyclin (IAP) in the treatment of pulmonary hypertension secondary to pulmonary embolism.
MedLine Citation:
PMID:  8708174     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe the use of inhaled aerosolized prostacyclin (IAP) in a patient with life-threatening pulmonary hypertension secondary to pulmonary embolism and to discuss the possible use of inhaled prostacyclin in the management of pulmonary embolism. DESIGN: Case report. SETTING: Intensive care unit of a university teaching hospital. PATIENTS: One patient with severe pulmonary hypertension secondary to acute-on-chronic pulmonary embolism. INTERVENTIONS: Conventional medical management of massive pulmonary embolism and inhaled aerosolized prostacyclin (IAP). MEASUREMENTS AND RESULTS: Description of clinical course, haemodynamic data and gas exchange data. CONCLUSIONS: We describe a patient with massive pulmonary embolism for whom the addition of IAP to his therapy appeared to result in a transient improvement in pulmonary haemodynamics and gas exchange.
S A Webb; S Stott; P V van Heerden
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  22     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-09-09     Completed Date:  1996-09-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  353-5     Citation Subset:  IM    
Department of Intensive Care, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
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MeSH Terms
Administration, Inhalation
Epoprostenol / therapeutic use*
Hypertension, Pulmonary / drug therapy*,  etiology
Pulmonary Embolism / complications*
Ventricular Dysfunction, Right / etiology
Reg. No./Substance:
0/Aerosols; 35121-78-9/Epoprostenol

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