Document Detail

The use of household cleaning products during pregnancy and lower respiratory tract infections and wheezing during early life.
MedLine Citation:
PMID:  23064260     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate the effects of household use of cleaning products during pregnancy on infant wheezing and lower respiratory tract infections (LRTI). METHODS: In four prospective Spanish birth cohorts (n = 2,292), pregnant women reported the use of household cleaning products. When infants were 12-18 months old, current cleaning product use and infant's wheezing and LRTI were reported. Cohort-specific associations between the use of specific products and respiratory outcomes were evaluated using multivariable regression analyses and estimates were combined using random-effects meta-analyses. RESULTS: The period prevalence of LRTI was higher when sprays (combined odds ratio (OR) = 1.29; 95 % confidence interval (CI) 1.04-1.59) or air fresheners (OR = 1.29; CI 1.03-1.63) were used during pregnancy. The odds of wheezing increased with spray (OR = 1.37; CI 1.10-1.69) and solvent (OR = 1.30; CI 1.03-1.62) use. The associations between spray and air freshener use during pregnancy and both outcomes remained apparent when these products were not used after pregnancy. Nevertheless, the estimates were higher when post-natal exposure was included. CONCLUSION: The use of cleaning sprays, air fresheners and solvents during pregnancy may increase the risk of wheezing and infections in the offspring.
Lidia Casas; Jan Paul Zock; Anne Elie Carsin; Ana Fernandez-Somoano; Ana Esplugues; Loreto Santa-Marina; Adonina Tardón; Ferran Ballester; Mikel Basterrechea; Jordi Sunyer
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-11
Journal Detail:
Title:  International journal of public health     Volume:  -     ISSN:  1661-8564     ISO Abbreviation:  Int J Public Health     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101304551     Medline TA:  Int J Public Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain,
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