Document Detail

The use of haloperidol and associated complications in the agitated, acutely ill pediatric burn patient.
MedLine Citation:
PMID:  15534454     Owner:  NLM     Status:  MEDLINE    
The use of haloperidol to induce sedation and control agitation in the acutely ill adult patient has been well documented. There are few reports, however, of the use of this neuroleptic agent to control the severe delirium and agitation that may occur in critically ill pediatric patients or acute pediatric patients suffering from burn wounds. We assessed the effectiveness and safety of the use of haloperidol by completing a retrospective chart review of 855 acutely ill children treated consecutively during the period from April 1999 to May 2002, during which time 26 children received haloperidol. The safe use of haloperidol was assessed by documenting any adverse effects or reactions observed after the administration of the drug. Of patients given haloperidol, 23% had adverse effects. This result suggests that the use of haloperidol to treat the acutely agitated and delirious pediatric burn patients is fraught with a number of difficulties and is not completely safe and effective.
Stephen L Ratcliff; Walter J Meyer; Luis J Cuervo; Cynthia Villarreal; Christopher R Thomas; David N Herndon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of burn care & rehabilitation     Volume:  25     ISSN:  0273-8481     ISO Abbreviation:  J Burn Care Rehabil     Publication Date:    2004 Nov-Dec
Date Detail:
Created Date:  2004-11-09     Completed Date:  2005-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8110188     Medline TA:  J Burn Care Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  472-8     Citation Subset:  IM    
Shriners Hospitals for Children, 815 Market Street, Galveston, TX 77550, USA.
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MeSH Terms
Anti-Dyskinesia Agents / administration & dosage,  adverse effects*
Burns / complications*
Critical Illness
Delirium / drug therapy*,  etiology
Dystonia / chemically induced
Fever / chemically induced
Haloperidol / administration & dosage,  adverse effects*
Psychomotor Agitation / drug therapy*,  etiology
Retrospective Studies
Reg. No./Substance:
0/Anti-Dyskinesia Agents; 52-86-8/Haloperidol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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