| The use of fluoxetine in Gilles de la Tourette syndrome and obsessive compulsive behaviours: preliminary clinical experience. | |
| | |
MedLine Citation:
|
PMID: 8843495 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
1. Obsessive Compulsive Behaviours (OCB) occur in more than 50% of patients with the Gilles de la Tourette Syndrome (GTS) and in some cases these behaviours are more disabling than the tics themselves. 2. Fluoxetine, a specific serotonin reuptake inhibitor (SSRI) has been demonstrated to be effective in patients with Obsessive Compulsive Disorder. 3. The authors report on their clinical experience of fluoxetine in 30 GTS patients with OCB, in an open retrospective study. 4. There was an overall improvement in OCB as judged by the clinician in 76% of cases. Most patients received fluoxetine at a daily dose of 20 to 40mg for an average period of 6 months (24 +/- 4 weeks). In general, fluoxetine was well tolerated and further studies are indicated. |
| | |
Authors:
|
V Eapen; M R Trimble; M M Robertson |
Related Documents
:
|
19114945 - Specific characteristics of the group psychotherapy of neurotic patients who survived w... 6945105 - The treatment of obsessional neurosis in a family setting. 1215455 - A concept of analytical treatment for patients with psychosomatic disorders. report on ... 738835 - The analytic introject and ego development. 8257975 - Nutritional factors in the pathogenesis and therapy of respiratory insufficiency in neu... 8534685 - Reduced blood levels of coagulation inhibitors in chronic hemodialysis compared with capd. |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Progress in neuro-psychopharmacology & biological psychiatry Volume: 20 ISSN: 0278-5846 ISO Abbreviation: Prog. Neuropsychopharmacol. Biol. Psychiatry Publication Date: 1996 May |
Date Detail:
|
Created Date: 1997-01-03 Completed Date: 1997-01-03 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8211617 Medline TA: Prog Neuropsychopharmacol Biol Psychiatry Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 737-43 Citation Subset: IM |
Affiliation:
|
Department of Neuropsychiatry, Institute of Neurology, London, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Antidepressive Agents, Second-Generation / adverse effects, therapeutic use* Child, Preschool Family Practice Female Fluoxetine / adverse effects, therapeutic use* Humans Male Obsessive-Compulsive Disorder / drug therapy*, psychology Psychiatric Status Rating Scales Retrospective Studies Tourette Syndrome / drug therapy*, psychology |
| Chemical | |
Reg. No./Substance:
|
0/Antidepressive Agents, Second-Generation; 54910-89-3/Fluoxetine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial.
Next Document: Benzodiazepines: tolerability in elderly patients.