Document Detail

The use of extracorporeal techniques to remove humoral factors in sepsis.
MedLine Citation:
PMID:  12656535     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine whether there is sufficient evidence of a benefit of hemofiltration or plasma filtration in sepsis. DATA SOURCES: Medline search, search of references in articles found in Medline search, literature known to local experts. STUDY SELECTION: Trials and reports where clinical outcome measures were included. DATA EXTRACTION: Clinically relevant information was presented. DATA SYNTHESIS: Studies were grouped according to hemofiltration or plasma filtration and within each of these groups into animal or human studies; then they were graded from case report, through case series, nonrandomized trials, and randomized trials. CONCLUSION: There is a lack of randomized trials. The available studies show an absence of benefit for hemofiltration. Further studies are needed in plasma filtration.
Paddy McMaster; Frank Shann
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  4     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-03-26     Completed Date:  2003-05-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2-7     Citation Subset:  IM    
Pediatric Intensive Care Unit, The Royal Children's Hospital, Melbourne, Australia.
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MeSH Terms
Cytokines / blood
Renal Dialysis*
Sepsis / blood*,  therapy*
Reg. No./Substance:

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