Document Detail

The use of dexmedetomidine to facilitate opioid and benzodiazepine detoxification in an infant.
MedLine Citation:
PMID:  15155322     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: Dexmedetomidine was used to facilitate opioid and benzodiazepine withdrawal in an 8-mo-old infant. A processed electroencephalogram (Bispectral Index) was used to guide the titration of dexmedetomidine in this neurologically impaired infant. This is the first report of dexmedetomidine use in an infant to manage chemical dependence withdrawal.
Julia C Finkel; Ahmed Elrefai
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  98     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-05-24     Completed Date:  2004-07-14     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1658-9, table of contents     Citation Subset:  AIM; IM    
Department of Anesthesiology, Children's National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USA.
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MeSH Terms
Analgesics, Opioid / pharmacokinetics,  therapeutic use*
Benzodiazepines / pharmacokinetics,  therapeutic use*
Dexmedetomidine / pharmacokinetics,  therapeutic use*
Electroencephalography / drug effects,  methods
Metabolic Detoxication, Drug / physiology
Substance Withdrawal Syndrome / drug therapy*,  metabolism,  physiopathology
Reg. No./Substance:
0/Analgesics, Opioid; 113775-47-6/Dexmedetomidine; 12794-10-4/Benzodiazepines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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