Document Detail

The use of captopril to control hypertension in post-transplant renal artery stenosis.
MedLine Citation:
PMID:  3891179     Owner:  NLM     Status:  MEDLINE    
Captopril is a new orally active angiotensin converting enzyme inhibitor that is useful for the treatment of hypertension. Prior reports have cautioned against its use for the control of blood pressure in patients with transplant renal artery stenosis since it caused a reversible renal failure. We describe a four year old child with radiographically proven transplant renal artery stenosis and severe hypertension that was safely managed with long-term administration of captopril. This case highlights the continued therapeutic role of this drug in the treatment of post-transplant hypertension, provided one carefully monitors the renal function in such patients.
H Trachtman; K M Butt; D Gordon; A Tejani
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  23     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1985 Apr 
Date Detail:
Created Date:  1985-08-09     Completed Date:  1985-08-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  203-6     Citation Subset:  IM    
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MeSH Terms
Captopril / therapeutic use*
Child, Preschool
Hypertension, Renovascular / drug therapy*,  etiology
Kidney Transplantation*
Postoperative Complications
Proline / analogs & derivatives*
Renal Artery Obstruction / complications,  etiology*,  radiography
Reg. No./Substance:
147-85-3/Proline; 62571-86-2/Captopril

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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