Document Detail

The use of bovine screws to promote bone formation using a tibia model in dogs.
MedLine Citation:
PMID:  23058228     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to evaluate the use of a unique resorbable bovine bone screw to stimulate bone formation. Bovine bone screws were inserted in the tibia of beagle dogs. Each animal received 8 screws, divided into groups A (screws + no membranes), B (screws + titanium reinforced membranes), and C (bone defects treated with autogenous bone grafts). Animals were killed at 2, 4, and 6 months. New bone was measured with a periodontal probe and reported an average of 7.4 mm in vertical bone gain for group B, 3.6 mm for group A, and 1.7 mm for group C. Submission to Kruskal-Wallis test showed statistical differences among groups (P < .05). Histologic examination revealed an intimate contact between the newly formed bone and the resorbing bone screws. We conclude that bovine bone screws provide an environment for new bone formation and thus may provide an alternative therapy for enhancing bone formation vertically, including for regenerative procedures as well as before implant therapy.
Marco Aurélio Bianchini; Marco Antônio B Pontual; Leonardo Bez; César Augusto M Benfatti; Fernanda Boabaid; Martha J Somerman; Ricardo S Magini
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2012-04-10
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology and oral radiology     Volume:  116     ISSN:  2212-4411     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-09-16     Completed Date:  2014-05-22     Revised Date:  2014-10-14    
Medline Journal Info:
Nlm Unique ID:  101576782     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e215-20     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
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MeSH Terms
Biocompatible Materials
Bone Regeneration / physiology*
Bone Screws*
Bone Transplantation / instrumentation,  methods*
Histological Techniques
Osseointegration / physiology*
Osteogenesis / physiology*
Grant Support
Reg. No./Substance:
0/Biocompatible Materials

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