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The use of biochemical assays in epidemiologic studies of reproduction.
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MedLine Citation:
PMID:  3691439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent progress in the assay of urinary hormones has opened new opportunities for epidemiologists to study hormones and health outcomes. This is especially true for studies of female reproduction. The cyclic nature of female reproduction can be fully described only by continuous frequent measurements that, in order to be practical, require easily collected biological specimens. We describe our experience in collecting and analyzing daily urine specimens from 301 healthy women. We conclude that this approach is not only feasible but potentially of great value to epidemiologists for studying fertility, early pregnancy, the effects of toxic exposures on reproduction, and the relationships between reproduction and later risk of chronic diseases.
Authors:
A J Wilcox; D D Baird; C R Weinberg; E G Armstrong; P I Musey; R E Wehmann; R E Canfield
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Environmental health perspectives     Volume:  75     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-02-20     Completed Date:  1988-02-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  29-35     Citation Subset:  IM    
Affiliation:
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.
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MeSH Terms
Descriptor/Qualifier:
Adult
Chorionic Gonadotropin / urine*
Coitus
Epidemiologic Methods
Estrogens / urine*
Female
Fertility
Humans
Luteinizing Hormone / urine*
Menstruation
Progesterone / urine*
Radioimmunoassay
Grant Support
ID/Acronym/Agency:
HD 15454/HD/NICHD NIH HHS; N01-ES-4-4054/ES/NIEHS NIH HHS; RR 00645/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Estrogens; 57-83-0/Progesterone; 9002-67-9/Luteinizing Hormone
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 11 Year: 1987
Volume: 75First Page: 29 Last Page: 35
ID: 1474432
PubMed Id: 3691439

The use of biochemical assays in epidemiologic studies of reproduction.
A J Wilcox
D D Baird
C R Weinberg
E G Armstrong
P I Musey
R E Wehmann
R E Canfield
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.



Article Categories:
  • Research Article


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