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The use of Onyx for embolization of peripheral vascular malformations in pediatric patients.
MedLine Citation:
PMID:  22270731     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: The management of congenital peripheral vascular malformations (VMs) can present a difficult therapeutic challenge. Endovascular transcatheter embolization of peripheral VMs is widely accepted as a first therapeutic option for many VMs. However, data describing the use of Onyx are limited in children with peripheral VMs. Our aim is to retrospectively evaluate the results of transcatheter arterial embolization with Onyx for peripheral VMs in children. MATERIALS AND METHODS: We analyzed clinical and imaging records of 16 patients who underwent 25 embolization procedures by using Onyx for peripheral VMs. In eight cases, embolization procedures were performed once; in seven cases, twice; and in one case, thrice. RESULTS: Embolization was technically complete in 4 patients and incomplete in 12 patients. Clinically, complete success was achieved in nine patients, and partial success was achieved in six patients. In one patient, reflux to the anterior and posterior tibial arteries caused peripheral ischemia, and the patient was referred to undergo plastic surgery. There were no complications in the other 15 patients. CONCLUSION: With future studies to better characterize the safety profile of this agent in peripheral vasculature, embolization with Onyx may become a valuable treatment option for peripheral VMs in pediatric patients.
Authors:
Murat Cantasdemir; Fatih Gulsen; Serdar Solak; Gokce Yalcin Gulsen; Fatih Kantarci; Furuzan Numan
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-22
Journal Detail:
Title:  Pediatric surgery international     Volume:  -     ISSN:  1437-9813     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8609169     Medline TA:  Pediatr Surg Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Interventional Radiology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey, muratcantasdemir@gmail.com.
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