Document Detail


The use of 99mc-EHDP as a scanning agent in the detection of metastases from osteosarcoma.
MedLine Citation:
PMID:  142718     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The early detection of metastatic spread in sixteen patients with osteosarcoma has been studied over a twelve month period, comparing the techniques of bone scanning and radiography. In only two patients were we able to demonstrate changes suggestive of pulmonary metastases any earlier with a 99mTc-EHDP scan than with chest radiographs and one of these resolved spontaneously. However, the bone scan did accurately delineate the extent of the primary tumour and may, therefore, be helpful in deciding the level of the amputation and the response of the patient to treatment, particularly now that chemotherapy and immunotherapy are frequently used in the management of the disease.
Authors:
S P Hughes; M K Benson; P J Ell; K E Britton
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin     Volume:  126     ISSN:  1438-9029     ISO Abbreviation:  Rofo     Publication Date:  1977 Jun 
Date Detail:
Created Date:  1977-10-14     Completed Date:  1977-10-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7507497     Medline TA:  Rofo     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  551-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Amputation Stumps
Bone Neoplasms / diagnosis*
Child
Epiphyses
Etidronic Acid / diagnostic use*
Female
Femoral Neoplasms / diagnosis
Humans
Lung Neoplasms / diagnosis*,  radiography
Male
Middle Aged
Neoplasm Metastasis
Osteosarcoma / diagnosis*
Radionuclide Imaging
Technetium / diagnostic use*
Chemical
Reg. No./Substance:
2809-21-4/Etidronic Acid; 7440-26-8/Technetium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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