Document Detail

The ureolytic microflora of immature dental plaque before and after rinsing with a urea-based mineralizing solution.
MedLine Citation:
PMID:  6589262     Owner:  NLM     Status:  MEDLINE    
Ureolytic bacteria were detected in the plaque flora of six subjects, and included members of the genera Actinomyces, Bifidobacterium, Staphylococcus, and Streptococcus. Proportions of these organisms did not change after subjects mouthrinsed thrice daily for four days with a plaque-mineralizing solution which contained urea and mono-fluorophosphate. The effectiveness of this rinse depends on the rapid metabolism of urea to alkali by plaque organisms, causing fluoridated apatite to precipitate in the matrix. Analysis of our data suggests that a numerically minor component of the flora, with a high turnover rate, is responsible for most of the ureolysis and the subsequent mineral precipitation.
I H Gallagher; E I Pearce; E M Hancock
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of dental research     Volume:  63     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-09-13     Completed Date:  1984-09-13     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1037-9     Citation Subset:  D; IM    
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MeSH Terms
Actinomyces / isolation & purification
Apatites / metabolism
Bacteria / isolation & purification*,  metabolism
Chemical Precipitation
Dental Plaque / microbiology*
Staphylococcus / isolation & purification
Streptococcus / isolation & purification
Urea / administration & dosage,  metabolism*
Reg. No./Substance:
0/Apatites; 0/Mouthwashes; 1306-05-4/fluorapatite; 57-13-6/Urea

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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