| An update of recent clinical trials examining adapalene and acne. | |
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MedLine Citation:
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PMID: 11843230 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Topical retinoids are a mainstay in the treatment of acne vulgaris. In the past these agents have been associated with irritant effects, however, newer generations of topical retinoids have emerged that have been designed to be less irritating. This paper focuses on the newer topical retinoid products, and specifically looks at adapalene and recent clinical studies that evaluate its efficacy and tolerability. Most of these studies evaluate adapalene in comparison with the new tretinoin formulations, which, like adapalene, have been designed to be less irritating than their predecessors. The various studies comparing the efficacy and tolerability of adapalene with the new formulations of tretinoin are described. A summary of the findings and their implications follows. |
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Authors:
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J E Wolf |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of the European Academy of Dermatology and Venereology : JEADV Volume: 15 Suppl 3 ISSN: 0926-9959 ISO Abbreviation: J Eur Acad Dermatol Venereol Publication Date: 2001 |
Date Detail:
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Created Date: 2002-02-14 Completed Date: 2002-07-31 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9216037 Medline TA: J Eur Acad Dermatol Venereol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 23-9 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Baylor College of Medicine, Houston, TX 77030-3411, USA. jwolf@bcm.tmc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
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diagnosis,
drug therapy* Administration, Topical Adolescent Adult Controlled Clinical Trials as Topic Female Follow-Up Studies Humans Male Naphthalenes / administration & dosage* Probability Treatment Outcome Tretinoin / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Naphthalenes; 106685-40-9/adapalene; 302-79-4/Tretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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