| An update on the hepatitis e virus. | |
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MedLine Citation:
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PMID: 23314803 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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There have been recent key advances in the understanding of hepatitis E virus infection. Since the early 1980s, when the virus was first discovered, hepatitis E has been described as a disease that is endemic only in the African and Asian subcontinents, a disease that is transmitted via the fecal-oral route, and a disease that causes an acute illness that typically resolves, with the exception of the third trimester of pregnancy, when infection can be deadly. We now know that genotype 3 is likely a porcine zoonotic disease that is quite prevalent in certain industrialized nations. Hepatitis E carries high morbidity and mortality in patients with underlying liver disease and can become a chronic infection that causes fibrosis in immunocompromised hosts. Lastly, two vaccines have been developed and studied in clinical trials, with excellent results. |
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Authors:
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Seth N Sclair; Eugene R Schiff |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current gastroenterology reports Volume: 15 ISSN: 1534-312X ISO Abbreviation: Curr Gastroenterol Rep Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888896 Medline TA: Curr Gastroenterol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 304 Citation Subset: IM |
Affiliation:
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Department of Medicine, Division of Hepatology, Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA, ssclair@med.miami.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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