Document Detail


An update on acute myocardial infarction from recent clinical trials.
MedLine Citation:
PMID:  9263655     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Exploration of new strategies and therapies to improve survival and outcomes of acute myocardial infarction (AMI) continues. Recently published large clinical trials, including the long-term results from Grampian Region Early Anistreplase Trial, Global Use of Strategies to Open Occluded Coronary Arteries, and the Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes (GUSTO-)IIb angioplasty substudy, have helped to clarify the relative benefits of earlier treatment, the use of third-generation thrombolytic agents, and the use of primary angioplasty. Other, smaller trials such as Evaluation of c7E3 Fab in Preventing ischemic Complications of High-risk Angioplasty and intracoronary Stenting and Antithrombotic Regimen have stimulated thoughts about new adjunctive agents and devices, including platelet glycoprotein IIb/IIIa antagonists, primary stenting, and antioxidants. Both knowledge and therapies have advanced significantly in the past year, which should improve clinical outcomes of AMI in the near future.
Authors:
A B Greenbaum; E M Ohman
Related Documents :
8221865 - Treatment of simple and complex coronary stenosis using rotational ablation followed by...
8279345 - Primary angioplasty for acute myocardial infarction in 1,000 consecutive patients. resu...
19067825 - Extraction of chronic pacing lead and angioplasty for complete superior baffle obstruct...
9637435 - Angioplasty of totally occluded old vein grafts with new interventional techniques: a l...
16727325 - Zona-penetration in vitro test for evaluating boar sperm fertility.
16352165 - Early definition of treatment outcomes after reperfusion therapy for myocardial infarct...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in cardiology     Volume:  12     ISSN:  0268-4705     ISO Abbreviation:  Curr. Opin. Cardiol.     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-09-23     Completed Date:  1997-09-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  418-26     Citation Subset:  IM    
Affiliation:
Duke Clinical Research Institute, Durham, NC 27705, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Clinical Trials as Topic / trends*
Humans
Myocardial Infarction* / drug therapy,  surgery,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical trials with implications regarding heart failure therapy.
Next Document:  Antiplatelet and antithrombin therapies in the acute coronary syndromes.