Document Detail


An unusual syndrome of a devastating noninflammatory vasculopathy associated with anticardiolipin antibodies: report of two cases.
MedLine Citation:
PMID:  3118887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe 2 patients with marked elevations of anticardiolipin antibodies who developed multiple-organ disease characterized by a noninflammatory vasculopathy. Their cases were remarkable for the fulminant nature of their thrombotic diathesis, which was heralded by a prominent livedo reticularis of the extremities. Both patients had a serologic profile and salivary gland biopsy findings that were consistent with a diagnosis of primary Sjögren's syndrome.
Authors:
S B Ingram; S H Goodnight; R M Bennett
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  30     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-12-11     Completed Date:  1987-12-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1167-72     Citation Subset:  AIM; IM    
Affiliation:
Division of Arthritis and Rheumatic Diseases, Oregon Health Sciences University, Portland 97201.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticoagulants / therapeutic use
Autoantibodies / analysis*
Blood Coagulation Factors / analysis,  immunology
Cardiolipins / immunology*
Combined Modality Therapy
Cyclophosphamide / therapeutic use
Enzyme-Linked Immunosorbent Assay
Female
Humans
Lupus Coagulation Inhibitor
Male
Plasmapheresis
Syndrome
Thrombosis / immunology*,  therapy
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Autoantibodies; 0/Blood Coagulation Factors; 0/Cardiolipins; 0/Lupus Coagulation Inhibitor; 50-18-0/Cyclophosphamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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