Document Detail


An unusual pulsed-wave tissue Doppler pattern in mitral valve prolapse: spikes on systolic velocities.
MedLine Citation:
PMID:  12174199     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Mitral valve prolapse (MVP) can be associated with wall-motion abnormalities. Pulsed-wave Doppler tissue imaging (DTI) has been proposed as a method to obtain myocardial velocities with a high spatial and temporal resolution. Our aim was to investigate whether a specific DTI pattern exists in myocardial segments of patients with MVP. METHODS AND RESULTS: We studied 49 consecutive patients with clinically suspected MVP. MVP was diagnosed in 35 patients. After recording the conventional echocardiographic variables, apical-directed left ventricular (LV) segmental myocardial velocities were obtained by DTI. The DTI analysis of myocardial segments revealed a distinct spectral Doppler pattern of mid- and basal posterior and lateral walls consistent with spikes on systolic velocities. These spikes were noticed in 23 (65%) patients with MVP but in none of the 14 subjects without MVP (P = 0.002). The MVP patients with spikes had larger mitral annulus diameters and higher amounts of maximal leaflet displacement when compared with those without spikes (34.8 +/- 5 mm vs 31.2 +/- 4 mm, P = 0.03 and 4.1 +/- 1 ms vs 3.1 +/- 1 mm, P = 0.01, respectively). CONCLUSION: This newly described unique DTI pattern, which may be observed in the majority of patients with MVP, may contribute to the diagnosis of disease. However, future studies are required to evaluate the clinical significance and pathophysiology of the spikes on systolic velocities of posterior and lateral walls in patients with MVP.
Authors:
Bahadir Dağdeviren; Osman Bolca; Mehmet Eren; Osman Akdemir; Erdinç Arikan; Yekta Gürlertop; Tuna Tezel
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  19     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-08-13     Completed Date:  2002-10-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  367-72     Citation Subset:  IM    
Affiliation:
Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey. bahadird@superonline.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cardiac Output / physiology
Case-Control Studies
Echocardiography, Doppler, Pulsed / methods*
Electrocardiography
Female
Heart Function Tests
Hemodynamics / physiology
Humans
Male
Middle Aged
Mitral Valve Prolapse / physiopathology*,  ultrasonography*
Myocardial Contraction / physiology*
Probability
Prospective Studies
Reference Values
Sensitivity and Specificity
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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