Document Detail

An unusual native tricuspid valve endocarditis caused by Candida colliculosa.
MedLine Citation:
PMID:  12667244     Owner:  NLM     Status:  MEDLINE    
Candida colliculosa, which grew in blood cultures of a 71-year-old retired man with fever of unknown origin that had lasted for 7 months, in conjunction with transthoracic echocardiography, demonstrating a 20-mm vegetation, superior to the tricuspid valve, herniating into the right atrial cavity. The finding led to the diagnosis of fungal endocarditis. Fluconazole, 600 mg daily, was commenced for 8 days; followed by amphotericin B, 1 mg/kg daily. On the fourth day of the amphotericin B treatment, the patient underwent replacement of the infected tricuspid valve. Even though the initial postoperative period was relatively uncomplicated, the patient died after a gross aspiration on the 67th day of his hospital stay, despite aggressive cardiovascular support and antimicrobial therapy. This is the first report of a native tricuspid valve fungal endocarditis due to C. colliculosa or Torulaspora delbrueckii, which is not known to be a human pathogen.
I Kaygusuz; L Mulazimoglu; N Cerikcioglu; A Toprak; A Oktay; V Korten
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases     Volume:  9     ISSN:  1198-743X     ISO Abbreviation:  Clin. Microbiol. Infect.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-01     Completed Date:  2003-06-03     Revised Date:  2006-11-07    
Medline Journal Info:
Nlm Unique ID:  9516420     Medline TA:  Clin Microbiol Infect     Country:  France    
Other Details:
Languages:  eng     Pagination:  319-22     Citation Subset:  IM    
Department of Medicine, Marmara University School of Medicine and Marmara Universitesi Hastanesi, Infeksiyon Hastaliklari ABD, 81090 Altunizade, Istanbul, Turkey.
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MeSH Terms
Amphotericin B / pharmacology,  therapeutic use
Candida / classification,  isolation & purification,  pathogenicity
Candidiasis / diagnosis*,  drug therapy,  microbiology
Endocarditis / diagnosis,  drug therapy,  microbiology*
Fluconazole / pharmacology,  therapeutic use
Tricuspid Valve / microbiology*
Reg. No./Substance:
1397-89-3/Amphotericin B; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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