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An unusual mimicker of a sepsis outbreak: ergot intoxication.
MedLine Citation:
PMID:  20972685     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within the first 6 h of life due to accidental administration of MEV instead of vitamin K in the delivery room. The major features of MEV poisoning were lethargy (41.7%), seizure (75.0%), feeding intolerance (66.6%), hypoventilation (58.3%), irritability (25%), and peripheral circulatory abnormalities (58.3%). As a conclusion, clinical findings of ergot toxicity in newborns cannot be distinguished from infectious disease or neonatal encephalopathy.
Authors:
Ahmet Yagmur Bas; Nihal Demirel; Ahmet Soysal; Kahraman Arslan; Ugur Dilmen
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Publication Detail:
Type:  Journal Article     Date:  2010-10-23
Journal Detail:
Title:  European journal of pediatrics     Volume:  170     ISSN:  1432-1076     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  633-7     Citation Subset:  IM    
Affiliation:
Department of Neonatology, Etlik Zubeyde Hanım Maternity and Teaching Hospital, Ankara, Turkey, yagmur32@yahoo.com.
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