| An unusual cause for sicca syndrome. | |
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MedLine Citation:
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PMID: 21654136 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We present a case of a 47-year-old female who presented with sicca symptoms since three months. As per the Revised International Classification Criteria for Sjögren's syndrome, patient was diagnosed as primary Sjögren's syndrome (SS). Patients with SS are known to have circulating monoclonal immunoglobulins. Serum electrophoresis revealed M band with serum gamma globulin concentration of 46 g/L. Bone marrow aspiration revealed 28% plasma cells. In absence of myeloma-related organ damage, a diagnosis of smouldering myeloma (MM) was made. Patient was treated with thalidomide and dexamethasone. Sicca symptoms resolved with anti-myeloma treatment. Although MM can occur as a complication of SS, MM can also rarely present as SS. In the present case, the short duration of sicca symptoms and response of these symptoms to anti-myeloma treatment support the diagnosis of MM presenting as SS. The present case highlights the importance of serum electrophoresis in patients presenting as SS. |
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Authors:
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U P Kulkarni; Y A Gokhale; P M Raut; R R Dargad |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of postgraduate medicine Volume: 57 ISSN: 0022-3859 ISO Abbreviation: J Postgrad Med Publication Date: 2011 Apr-Jun |
Date Detail:
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Created Date: 2011-06-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985196R Medline TA: J Postgrad Med Country: India |
Other Details:
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Languages: eng Pagination: 129-30 Citation Subset: IM |
Affiliation:
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Department of Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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