| An unusual cause of sepsis during pregnancy: recognizing infection with chlamydophila abortus. | |
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MedLine Citation:
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PMID: 16260577 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Chlamydophila abortus (formerly Chlamydia psittaci serovar 1) is a rare but severe cause of gestational septicemia, with particular problems in diagnosis and clinical management. CASE: A 32-year-old woman in her fourth pregnancy (16th week of gestation) presented with progressive septicemia after extensive contact with abortive material from her goat flock. Treatment with levofloxacin could not prevent abortion. Multiorgan failure requiring catecholamines and artificial ventilation developed in the patient. After the agent was identified by polymerase chain reaction from acute-phase serum, macrolides were administered and yielded clinical improvement. The patient fully recovered. There were no sequelae in the subsequent 6 months. CONCLUSION: Cp abortus must be considered in gestational septicemia after contact with ruminants. Polymerase chain reaction from acute-phase serum is a quick and easy way to establish the diagnosis. Macrolide antibiotics are still the treatment of choice. |
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Authors:
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Gernot Walder; Helmut Hotzel; Christoph Brezinka; Walter Gritsch; Robert Tauber; Reinhard Würzner; Franz Ploner |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 106 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-11-01 Completed Date: 2006-02-03 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1215-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Hygiene and Social Medicine, Medical University of Innsbruck, Innsbruck, Austria, and Department of Anesthesiology, Regional Hospital of Sterzing, Sterzing, Italy. gernot.walder@uibk.ac.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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microbiology* Adult Animals Chlamydophila psittaci / isolation & purification, pathogenicity Female Goat Diseases / microbiology*, transmission Goats Humans Macrolides / therapeutic use Ofloxacin / therapeutic use Pregnancy Pregnancy Complications, Infectious / diagnosis, drug therapy, microbiology* Psittacosis / complications*, diagnosis, drug therapy, microbiology Risk Factors Sepsis / complications*, diagnosis, drug therapy Zoonoses* |
| Chemical | |
Reg. No./Substance:
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0/Macrolides; 82419-36-1/Ofloxacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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