| An unusual cause of posterior fossa mass: Lhermitte-Duclos disease. | |
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MedLine Citation:
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PMID: 20060133 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lhermitte-Duclos disease (LDD) (dysplastic cerebellar gangliocytoma) is a rare disorder of unknown pathogenesis, presenting with signs and symptoms resulting from obstruction of cerebrospinal fluid flow and mass effect in the posterior fossa. Magnetic resonance imaging is the diagnostic modality of choice allowing preoperative diagnosis with characteristic findings. Surgery is the choice of treatment. The typical histopathological findings of LDD are characterized by widening of the molecular layer, absence of the Purkinje cell layer and hypertrophy in the granule cell layer. Herein we report an adolescent girl with LDD diagnosed preoperatively by the conventional and advanced MR techniques. |
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Authors:
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Beg?l Ya?ci-K?peli; Kader K Oguz; M Asim Bilen; Bilgehan Yal?in; Nejat Akalan; M?nevver B?y?kpamuk?u |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-01-08 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 290 ISSN: 1878-5883 ISO Abbreviation: J. Neurol. Sci. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 138-41 Citation Subset: IM |
Affiliation:
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Department of Pediatric Oncology, Hacettepe University Institute of Oncology, 06100 Ankara, Turkey. drbegul@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Cerebellar Neoplasms / pathology*, physiopathology, radiography Cerebellum / pathology*, physiopathology, radiography Cranial Fossa, Posterior / pathology*, physiopathology Female Fourth Ventricle / pathology, physiopathology, radiography Hamartoma Syndrome, Multiple / pathology*, physiopathology, radiography Headache / etiology Humans Hydrocephalus / pathology, physiopathology, radiography Intracranial Hypertension / etiology, pathology, physiopathology Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Neurosurgical Procedures Tomography, X-Ray Computed Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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