| An unusual case of subclinical diffuse glucagonoma coexisting with two nodules in the pancreas: Characteristic features on computed tomography. | |
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MedLine Citation:
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PMID: 22239827 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A lesion was discovered in the tail of the pancreas by ultrasonography performed during a health checkup for a 59-year-old Japanese man. Abdominal contrast-enhanced computed tomography (CE-CT) revealed strong enhancement in a 4-cm tumor in the pancreatic tail and in a 1-cm tumor in the pancreatic body. Serum glucagon levels were elevated to 54,405pg/mL and a preoperative diagnosis of glucagonoma was made. The pancreatic tail and spleen were resected en bloc, along with a protruding tumor in the pancreatic body. However, histopathological evaluation revealed diffuse glucagonoma throughout the pancreas. When we retrospectively reviewed abdominal CE-CT after the operation, the entire pancreas was seen to be enlarged and diffusely enhanced by strong spots. Immunohistochemical examination using anti-CD31 demonstrated rich microvessels in two solid glucagonomas as well as microglucagonoma throughout the entire pancreas, indicating hypervascularity. Enlarged pancreas and diffuse enhancement of the pancreas by strong spots may be characteristic features of diffuse glucagonoma on abdominal CE-CT. |
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Authors:
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N Azemoto; T Kumagi; T Yokota; T Kuroda; M Koizumi; H Yamanishi; Y Soga; S Furukawa; M Abe; Y Ikeda; Y Hiasa; B Matsuura; J Watanabe; F Kushihata; M Onji |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-10 |
Journal Detail:
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Title: Clinics and research in hepatology and gastroenterology Volume: - ISSN: 2210-741X ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101553659 Medline TA: Clin Res Hepatol Gastroenterol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Endoscopy Center, Ehime University Hospital, Shitsukawa, Toon, Ehime, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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