| An unusual case of an osteosarcoma arising in a leiomyoma of the uterus. | |
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MedLine Citation:
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PMID: 22634486 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Leiomyoma is the most common uterine neoplasm. It has several histological variants such as atypical, cellular, myxoid, and epithelioid. Leiomyoma with heterologous elements is a rare variant of leiomyoma, which may contain heterologous elements such as fat, skeletal muscle, and chondroid and osseous tissues. The heterologous sarcomatous differentiation is also rarely seen. We report on a 53-year-old woman who was admitted with abnormal vaginal bleeding and symptoms related to an abdominal mass. She had a huge uterine leiomyoma that contained osteosarcomatous differentiation in several foci. Although malignant progression for leiomyoma is exceedingly rare, when it occurs it may result not only in a leiomyosarcoma but also in a heterologous sarcomatous differention. We have reported histopathological, immunohistochemical, and clinical features of this rare case and reviewed the published studies. |
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Authors:
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M Kefeli; S Baris; O Aydin; L Yä Ldä Z; S Yamak; B Kandemir |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-23 |
Journal Detail:
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Title: Annals of Saudi medicine Volume: - ISSN: 0975-4466 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8507355 Medline TA: Ann Saudi Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pathology, Ondokuz Mayis University, Medical School, Gazi State Hospital, Samsun, Turkey mehmetkefeli@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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