Document Detail


An unusual case of POEMS syndrome.
MedLine Citation:
PMID:  3570737     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 58-year-old woman presented with a history of premature onset of menopause, longstanding hepatosplenomegaly, monoclonal gammopathy, lower limb polyneuropathy of recent onset, diabetes mellitus, excessive perspiration and leg edema. Polyneuropathy and excessive perspiration improved following a course of prednisone and melphalan. The clinical and pathophysiological features fit the rare entity known as POEMS syndrome.
Authors:
E Sigler; D Modai; R Zaidenstein; A Golik; E L Marcus; N Cohen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Israel journal of medical sciences     Volume:  22     ISSN:  0021-2180     ISO Abbreviation:  Isr. J. Med. Sci.     Publication Date:  1986 Dec 
Date Detail:
Created Date:  1987-06-12     Completed Date:  1987-06-12     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0013105     Medline TA:  Isr J Med Sci     Country:  ISRAEL    
Other Details:
Languages:  eng     Pagination:  906-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Drug Therapy, Combination
Female
Hepatomegaly / complications*
Humans
Hypergammaglobulinemia / complications*
Immunoglobulin G*
Melphalan / administration & dosage
Middle Aged
Monoclonal Gammopathy of Undetermined Significance / complications*
Polyneuropathies / complications*,  drug therapy
Prednisone / administration & dosage
Syndrome
Chemical
Reg. No./Substance:
0/Immunoglobulin G; 148-82-3/Melphalan; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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