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An unusual case of Crohn's disease with unresponsive pleural exudates. Is Crohn's disease finally a systemic immunological disorder?
MedLine Citation:
PMID:  21172193     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Crohn's disease has been infrequently associated with various respiratory manifestations. Reports of pleural effusions in Crohn's disease are even sparser, but differential diagnosis is rich, with causes either associated with the disease or being independent. Processes directly or indirectly related to therapy, entities overlapping with Crohn's disease in pathogenesis and common causes of effusions should all be considered, under the guidance of laboratory testing and imaging. We report here an unusual case of bilateral pleural effusions unresponsive so far to medical therapy, in a patient with long-standing Crohn's disease and several features of autoimmunity. A short review of the literature is presented, the differential diagnosis is outlined and the systemic immunological profile of Crohn's disease is discussed.
Authors:
Athanasios A Papathanasopoulos; Konstantinos H Katsanos; Dimitrios K Christodoulou; Spyridon Nikas; Epameinondas V Tsianos
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Publication Detail:
Type:  Journal Article     Date:  2007-09-25
Journal Detail:
Title:  Journal of Crohn's & colitis     Volume:  1     ISSN:  1873-9946     ISO Abbreviation:  J Crohns Colitis     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2010-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101318676     Medline TA:  J Crohns Colitis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  116-21     Citation Subset:  -    
Affiliation:
Department of Internal Medicine and Hepato-Gastroenterology Unit, Medical School, University of Ioannina, Ioannina, Greece.
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