| An unreported complication of intravenously administered ibuprofen: gastrointestinal bleeding. | |
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MedLine Citation:
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PMID: 22530348 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Ibuprofen is used for the closure of ductus arteriosus either intravenously or enterally. Although intraventricular hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia, transient renal failure, oliguria, hyponatremia and thrombocytopenia are reported complications during or after ibuprofen treatment, gastrointestinal bleeding, to our knowledge, has not been reported previously. We herein report a premature newborn, in whom ibuprofen was used intravenously for the closure of ductus arteriosus and gastrointestinal bleeding developed as a complication, and aim to discuss this rare adverse effect. In conclusion, we emphasize the importance of close follow-up of premature newborns during intravenous ibuprofen treatment considering also the other rare systemic side effects reported in the literature. |
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Authors:
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S U Sarici; O Dabak; K Erdinc; V Okutan; M K Lenk |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European review for medical and pharmacological sciences Volume: 16 ISSN: 1128-3602 ISO Abbreviation: Eur Rev Med Pharmacol Sci Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-04-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9717360 Medline TA: Eur Rev Med Pharmacol Sci Country: Italy |
Other Details:
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Languages: eng Pagination: 325-7 Citation Subset: IM |
Affiliation:
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Division of Neonatology, Gulhane Military Medical Academy, Ankara, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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