Document Detail

A unique fucoganglioside with blood group B determinant in rat spleen.
MedLine Citation:
PMID:  2292597     Owner:  NLM     Status:  MEDLINE    
A unique fucoganglioside was isolated from rat spleen and characterized by compositional analysis, methylation analysis, exoglycosidase treatment, negative ion fast atom bombardment (FAB) mass spectrometry, and proton NMR spectrometry. The ganglioside was identified as alpha Gal,Fuc-GM1(NeuGc), which has the blood group B determinant at the nonreducing termini, as shown below: (formula; see text) This is the first report describing the occurrence in nature of alpha Gal,Fuc-GM1 containing N-glycolylneuraminic acid.
K Nohara; M Suzuki; F Inagaki; H Ito; K Kaya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biochemistry     Volume:  108     ISSN:  0021-924X     ISO Abbreviation:  J. Biochem.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-04-08     Completed Date:  1991-04-08     Revised Date:  2007-12-19    
Medline Journal Info:
Nlm Unique ID:  0376600     Medline TA:  J Biochem     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  684-8     Citation Subset:  IM    
National Institute for Environmental Studies, Ibaraki.
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MeSH Terms
ABO Blood-Group System*
Carbohydrate Sequence
Fatty Acids / analysis
Gangliosides / isolation & purification*
Molecular Sequence Data
Rats, Inbred Strains
Spleen / chemistry*
Reg. No./Substance:
0/ABO Blood-Group System; 0/Fatty Acids; 0/Gangliosides; 0/fucogangliosides

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