Document Detail

An unexpectedly high rate of pulmonary embolism in patients with superficial thrombophlebitis of the thigh.
MedLine Citation:
PMID:  10587397     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The rate of objectively proven pulmonary embolism in patients with thrombophlebitis of the greater saphenous vein was studied.
METHODS: Consecutive ambulant patients with thrombophlebitis of the greater saphenous vein, involving the above-knee segment, underwent a complete venous echo color Doppler examination of the lower limbs, perfusion lung scanning, and chest radiography. A high probability of pulmonary embolism was defined as the presence of two or more large segmental defects, one large and two or more moderate perfusion defects, or four or more moderate perfusion defects, with no corresponding abnormality found by means of chest radiography.
RESULTS: Of the 21 patients included in the study, findings compatible with a high probability of pulmonary embolism were detected in seven patients (33.3%; 95% CI, 14.6 to 57. 0), although clinical symptoms of pulmonary embolism were present only in one patient. No association was found between the presence of thrombosis at the saphenofemoral junction and the risk for pulmonary embolism.
CONCLUSION: The rate of pulmonary embolism in patients with thrombophlebitis of the greater saphenous vein is unexpectedly high. This risk is similarly high in patients with thrombosis at the saphenofemoral junction and in patients without thrombosis at the saphenofemoral junction. Our results are consistent with those of other recent investigations and suggest that superficial thrombophlebitis of the thigh is not as benign a disease entity as previously described.
F Verlato; P Zucchetta; P Prandoni; G Camporese; M C Marzola; G Salmistraro; F Bui; R Martini; F Rosso; G M Andreozzi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  30     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  1999-12-30     Completed Date:  1999-12-30     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1113-5     Citation Subset:  IM    
Unit Care of Angiology, University Hospital of Padua, Padova, Italy.
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MeSH Terms
Aged, 80 and over
Diagnostic Imaging
Middle Aged
Pulmonary Embolism / diagnosis*,  epidemiology
Saphenous Vein*
Thigh / blood supply
Thrombosis / diagnosis*,  epidemiology

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