Document Detail

An unexpected ending: brain death following acute severe asthma.
MedLine Citation:
PMID:  18798723     Owner:  NLM     Status:  MEDLINE    
A 56-year-old woman presented to our hospital with acute severe asthma. As a consequence of severe refractory airflow limitation, moderate hypercapnia ensued for several days. Unexpectedly, the patient died as a result of brain stem herniation, in the absence of hypoxaemia, arterial hypotension or an intracranial mass lesion. We discuss the mechanisms that may have precipitated severe intracranial hypertension resulting in brain death, and the possible methods to detect and avoid such a devastating consequence.
Steven T Galluccio; Sumeet Rai; Peter Sharley
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine     Volume:  10     ISSN:  1441-2772     ISO Abbreviation:  Crit Care Resusc     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-18     Completed Date:  2008-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888170     Medline TA:  Crit Care Resusc     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  IM    
Intensive Care Unit, Royal Adelaide Hospital, Adelaide, SA, Australia.
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MeSH Terms
Brain Edema / etiology*,  pathology
Fatal Outcome
Intracranial Hypertension / etiology*,  pathology
Middle Aged
Status Asthmaticus / complications*,  diagnosis,  therapy

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