Document Detail


An uncommon adverse effect of levodopa withdrawal in a patient taking antipsychotic medication: neuroleptic malignant-like syndrome.
MedLine Citation:
PMID:  21282831     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient with symptoms suggestive of neuroleptic malignant syndrome after levodopa withdrawal is described. The patient presented with persistent high fever, stupor, autonomic dysfunction, rigidity, and rhabdomyolysis. He was successfully treated with intravenous dantrolene, resumption of levodopa, and forced alkaline diuresis. Doctors should be aware of the risk of abrupt cessation of dopamine agonists.
Authors:
S P Man
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine     Volume:  17     ISSN:  1024-2708     ISO Abbreviation:  Hong Kong Med J     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-01     Completed Date:  2011-05-18     Revised Date:  2011-05-20    
Medline Journal Info:
Nlm Unique ID:  9512509     Medline TA:  Hong Kong Med J     Country:  China    
Other Details:
Languages:  eng     Pagination:  74-6     Citation Subset:  IM    
Affiliation:
Department of Medicine and Geriatrics, Tuen Mun Hospital, Tuen Mun, Hong Kong. spiuman@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Antipsychotic Agents / adverse effects*
Dopamine Agonists / adverse effects*
Humans
Levodopa / adverse effects*
Male
Neuroleptic Malignant Syndrome / diagnosis,  etiology*
Substance Withdrawal Syndrome / etiology*
Chemical
Reg. No./Substance:
0/Antipsychotic Agents; 0/Dopamine Agonists; 0/Levodopa
Comments/Corrections
Comment In:
Hong Kong Med J. 2011 Apr;17(2):167-8   [PMID:  21471604 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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