Document Detail

The ultraviolet light and photosensitized inactivation of tobacco mosaic virus.
Jump to Full Text
MedLine Citation:
PMID:  15409511     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The quantum yield for the inactivation of tobacco mosaic virus has been determined at 253.7 mmicro and found to be 4.3 x 10(-6). The possible significance of the observed one-hit process of inactivation has been discussed in terms of the kinetics and the rupture of model substances including nucleic acid. The ultraviolet light inactivation, which proceeds independent of oxygen, occurs without change in physicochemical properties, with the possible exception of an enhanced sensitivity to thermal denaturation. The photosensitized inactivation of virus by acriflavine has been found to proceed parallel with the destruction of the dye. The action was found to be dependent upon adsorbed dye, and the inactivation is enhanced by the presence of oxygen.
Authors:
G OSTER; A D McLEAN
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of general physiology     Volume:  33     ISSN:  0022-1295     ISO Abbreviation:  J. Gen. Physiol.     Publication Date:  1950 Jan 
Date Detail:
Created Date:  1950-12-01     Completed Date:  2004-09-30     Revised Date:  2010-09-20    
Medline Journal Info:
Nlm Unique ID:  2985110R     Medline TA:  J Gen Physiol     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  215-28     Citation Subset:  OM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Ultraviolet Rays*
Viruses*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Gen Physiol
ISSN: 0022-1295
ISSN: 1540-7748
Publisher: The Rockefeller University Press
Article Information
Download PDF
Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research
Received Day: 5 Month: 8 Year: 1949
Print publication date: Day: 20 Month: 1 Year: 1950
Volume: 33 Issue: 3
First Page: 215 Last Page: 228
ID: 2147152
PubMed Id: 15409511

THE ULTRAVIOLET LIGHT AND PHOTOSENSITIZED INACTIVATION OF TOBACCO MOSAIC VIRUS
Gerald Oster
A. Douglas McLaren
From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, New Jersey, and the Institute of Polymer Research, Polytechnic Institute of Brooklyn, Brooklyn, New York


Article Categories:
  • Article


Previous Document:  Dehydrogenated alkaloids of ergot in treatment of peripheral vascular diseases.
Next Document:  Methyl green-pyronin; stoichiometry of reaction with nucleic acids.