| The ultrastructure of cardiac desnosomes in the toad and their relationship to the intercalated disc. | |
| | |
| Jump to Full Text | |
MedLine Citation:
|
PMID: 13708707 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The fine structure of desmosomes and intercalated discs in the toad heart is discussed. A definite relationship between the dense components of these structures and the dense region of the Z band is demonstrated. The dense region of the Z band characteristically widens at its approach to the plasma membrane, and often terminates beneath it in a distinct discoidal plaque. Cardiac desmosomes appear to be structures which result from the intimate apposition of plaques of Z band material. These desmosomes retain the Z band function as sites of attachment for myofilaments. The suggestion is made that rotation of a desmosome through 90 degrees and splitting of filaments from the adjacent sarcomere could result in the formation of a simple step-like intercalated disc. Intermediate stages in this process are illustrated. Complex discs present in the toad probably represent the alignment of groups of simple discs produced by contractile forces. Possible physiologic functions of the disc and desmosome are discussed. Other morphologic features of toad cardiac cells include a distinct amorphous outer coat to the sarcolemma, a prominent N band, and a granular sarcoplasm with poorly developed reticulum. |
| | |
Authors:
|
P M GRIMLEY; G A EDWARDS |
Related Documents
:
|
22740057 - Cardiac rhythm disturbances associated with amlodipine acute intoxication. 19319187 - Glutathione deficiency in cardiac patients is related to the functional status and stru... 22319537 - Pure motor monoparesis in the leg due to a lateral medullary infarction. 22457167 - Unmasking of myopotential oversensing by an integrated bipolar defibrillator lead follo... 12377607 - Pathological q-wave generation in light of the q wave alteration resulting from myocard... 10588777 - In vitro, animal, and human characterization of optison infusions for myocardial contra... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of biophysical and biochemical cytology Volume: 8 ISSN: 0095-9901 ISO Abbreviation: J Biophys Biochem Cytol Publication Date: 1960 Oct |
Date Detail:
|
Created Date: 1961-12-01 Completed Date: 1998-11-01 Revised Date: 2010-06-22 |
Medline Journal Info:
|
Nlm Unique ID: 17840020R Medline TA: J Biophys Biochem Cytol Country: Not Available |
Other Details:
|
Languages: eng Pagination: 305-18 Citation Subset: OM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Heart
/
anatomy & histology* |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
|
Journal Information Journal ID (nlm-ta): J Biophys Biochem Cytol ISSN: 0095-9901 Publisher: The Rockefeller University Press |
Article Information Download PDF  Copyright © Copyright 1961 by The Rockefeller Institute Press Received Day: 12 Month: 8 Year: 1959 Print publication date: Day: 1 Month: 10 Year: 1960 Volume: 8 Issue: 2 First Page: 305 Last Page: 318 ID: 2224943 PubMed Id: 13708707 |
| THE ULTRASTRUCTURE OF CARDIAC DESMOSOMES IN THE TOAD AND THEIR RELATIONSHIP TO THE INTERCALATED DISC | |
| Philip M. Grimley | |
| George A. Edwards | |
| From The Division of Laboratories and Research, New York State Department of Health, Albany |
|
Article Categories:
|
|
Previous Document: True anomalous osmosis in multi-solute model membrane systems.
Next Document: Endemic treponematoses in the Sudan. A report on a survey.